Advanced paternal age does not affect embryo aneuploidy in egg donor cycles
نویسندگان
چکیده
منابع مشابه
High percentages of embryos with 21, 18 or 13 trisomy are related to advanced paternal age in donor egg cycles
OBJECTIVE Advanced paternal age is related to poor sperm quality; however, little is known on its effect on aneuploidy embryo rates and, more importantly, on chromosomal abnormalities like trisomy 21, 18 and 13. The objective of this study was to evaluate the effect of advanced paternal age on the trisomy rates of the chromosomes 21, 18 or 13 in embryos obtained from donated oocytes. METHODS ...
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There is general acceptance that mixing sows during the first 3 weeks of gestation is detrimental to embryo development and survival. However, there is a paucity of data describing the influence of group housing and remixing during the first 14 days of gestation on pregnancy outcomes. Using 96 purebred maternal (Large White)/terminal (Duroc) line gilts, the current study determined the effects ...
متن کاملDonor Gender Does Not Affect Liver Transplantation Outcome in Children
The liver is recognized as a sex hormone-responsive organ. Gender-specific differences in liver function are known to exist. Recently, a higher failure rate for organs transplanted in adults from female donors to male recipients has been reported. This increased failure rate of livers obtainedfrom adult females and transplanted into adult males is thought to occur, at least in part, as a result...
متن کاملHigh Aneuploidy Rates Observed in Embryos Derived from Donated Oocytes are Related to Male Aging and High Percentages of Sperm DNA Fragmentation
CAPSULE Male aging effects on aneuploidy rates in embryos. OBJECTIVE Paternal age is associated with decreasing sperm quality; however, it is unknown if it influences chromosomal abnormalities in embryos. The objective of this study is to evaluate if the aneuploidy rates in embryos are affected by advanced paternal age. METHODS A total of 286 embryos, obtained from 32 in vitro fertilization...
متن کاملThe combination of polar body and embryo biopsy does not affect embryo viability.
BACKGROUND The biopsy of both polar bodies and a blastomere from the same embryo was investigated as an approach aimed at increasing the quantity of DNA available for genetic analysis in preimplantation embryos. METHODS In 113 cycles, preimplantation genetic diagnosis (PGD) was performed for aneuploidy: 19 cycles underwent polar body biopsy, 32 cycles had both polar body and blastomere biopsy...
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ژورنال
عنوان ژورنال: Fertility and Sterility
سال: 2018
ISSN: 0015-0282
DOI: 10.1016/j.fertnstert.2018.07.327